The solid collar needle roller bearing has compact structure, small radial size and large load carrying capacity. It is suitable for the parts of which the radial overall size is limited. It is also wide applied to the situation where the shaft or housing has the swinging motion. In general, the needle roller bearing only withstands the radial load, not the axial load. When the shaft has axial load, it can be used in combination with other bearings. However, it does not limit the axial shift of shaft or housing. The limiting rotational speed of needle roller bearing is lower. In high rotational speed of main machine, the needle roller bearing with cage shall be chosen as far as possible. In compassion with other types of needle roller bearings, under the situation of same radial size, the needle roller bearing has the large load carrying capacity and high rigidity but has high friction torque.
This kind of bearing has many series with different structure and size. It is requested that the hardness, processing accuracy and surface roughness of shaft journal surface and rolling surface of outer housing be same as those of the collar of bearing. As for the needle roller with G2 class, the diameter varies within 2μm in group. Except the full complement needle roller bearings, they have the rigid cages, which can correctly guide the parallel axis line of needle roller.
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Gut is a leading international journal in gastroenterology and hepatology and has an established reputation for publishing first class clinical research of the alimentary tract, the liver, biliary tree and pancreas. Gut delivers up-to-date, authoritative, clinically oriented coverage in all areas of gastroenterology and hepatology. Regular features include articles by leading authorities describing novel mechanisms of disease and new management strategies, both diagnostic and therapeutic, likely to impact on clinical practice within the foreseeable future.
Our new online collection highlights all research relating to the COVID-19 pandemic published by Gut, Frontline Gastroenterology and BMJ Open Gastroenterology. It is updated regularly as new articles are published.
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Spatial profiling of gastric cancer metastases reveals principles of tumour dissemination
To cite: Sundar R, Liu DH, Hutchins GG, et al. Gut 2021;70:1823-1832.
Read the full article here: link
Objective: Endoscopic mucosal biopsies of primary gastric cancers (GCs) are used to guide diagnosis, biomarker testing and treatment. Spatial intratumoural heterogeneity (ITH) may influence biopsy-derived information. We aimed to study ITH of primary GCs and matched lymph node metastasis.
Conclusions: In GC, regional lymph node metastases are likely to originate from deeper subregions of the primary tumour. Future clinical trials of novel targeted therapies must consider assessment of deeper subregions of the primary tumour and/or metastases as several therapeutically relevant genes are only mutated, overexpressed or amplified in these regions.